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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM50B
All Species:
18.79
Human Site:
S118
Identified Species:
37.58
UniProt:
Q9Y247
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y247
NP_036267.1
325
38709
S118
R
E
R
K
R
K
I
S
C
L
S
F
A
L
D
Chimpanzee
Pan troglodytes
XP_001146118
452
50373
S231
K
E
A
K
R
K
I
S
S
L
S
F
T
L
E
Rhesus Macaque
Macaca mulatta
XP_001093508
325
38467
S118
K
E
A
K
R
K
I
S
S
L
S
F
T
L
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTJ8
334
39575
S118
R
E
R
K
R
K
I
S
N
L
S
F
T
L
D
Rat
Rattus norvegicus
NP_001100819
335
39649
S118
R
E
R
K
R
K
I
S
N
L
S
F
T
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518058
312
37095
S81
K
E
E
K
R
K
I
S
S
L
S
F
T
L
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q2VPH1
340
40315
A118
K
E
Q
K
R
K
I
A
S
L
S
F
N
L
E
Zebra Danio
Brachydanio rerio
Q568K9
341
40523
A118
E
E
Q
K
R
K
I
A
S
L
S
F
N
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAY7
359
42838
Q117
N
K
Q
K
R
Q
I
Q
A
L
S
F
N
L
D
Honey Bee
Apis mellifera
XP_624083
345
40901
Q117
N
K
Q
K
K
Q
I
Q
A
L
S
F
N
L
Y
Nematode Worm
Caenorhab. elegans
Q18691
326
37886
R115
V
A
K
H
T
Q
K
R
F
L
S
F
A
F
D
Sea Urchin
Strong. purpuratus
XP_001183761
318
37639
G110
K
K
K
L
K
N
A
G
T
L
S
F
N
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.4
78.1
N.A.
N.A.
83.8
83.8
N.A.
55.6
N.A.
71.7
70
N.A.
54.5
53.6
44.1
58.4
Protein Similarity:
100
66.1
91.6
N.A.
N.A.
93.1
92.2
N.A.
69.2
N.A.
87.3
85.9
N.A.
74.9
77.3
66.2
81.5
P-Site Identity:
100
66.6
66.6
N.A.
N.A.
86.6
86.6
N.A.
73.3
N.A.
60
60
N.A.
53.3
40
33.3
26.6
P-Site Similarity:
100
80
80
N.A.
N.A.
86.6
86.6
N.A.
80
N.A.
86.6
73.3
N.A.
73.3
66.6
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
0
0
0
9
17
17
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% D
% Glu:
9
67
9
0
0
0
0
0
0
0
0
0
0
0
25
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
100
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
84
0
0
0
0
0
0
0
0
% I
% Lys:
42
25
17
84
17
67
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
100
0
0
0
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
17
0
0
0
0
9
0
0
17
0
0
0
42
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
34
0
0
25
0
17
0
0
0
0
0
0
0
% Q
% Arg:
25
0
25
0
75
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
42
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
9
0
0
0
42
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _